DYRK2 Polyclonal Antibody, 20ul Site-directed Mutagenesis The protein encoded by this

The protein encoded by this gene mediates calcium entry| and this entry is potentiated by calcium store depletion

and functions as a tumor suppressor in multiple types of cancer

Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase

and transcription-coupled DNA repair

RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al

DYRK2 Polyclonal Antibody, 20ul Site-directed Mutagenesis The protein encoded by thisDYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1,