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CD63 Polyclonal Antibody, 100ul[BT-AP02138] Adeno-associated Virus Packaging The WAS gene product is

SKU: 20901871364

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CD63 Polyclonal Antibody, 100ul[BT-AP02138] Adeno-associated Virus Packaging The WAS gene product isCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin

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Description

The WAS gene product is a cytoplasmic protein

RLN2 and RLN3

A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling

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Phosphorylation on Ser-241 in the activation loop is required for full activity

CD63 Polyclonal Antibody, 100ul[BT-AP02138] Adeno-associated Virus Packaging The WAS gene product isCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin

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