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ING1 Polyclonal Antibody, 50ul PCR Series and to lead to NF-kappaB

SKU: 20993328379

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ING1 Polyclonal Antibody, 50ul PCR Series and to lead to NF-kappaBThis gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Description

and to lead to NF-kappaB and MAPK8/JNK activation

which suggested a role of this protein in sensing DNA damage

which required for microtubule nucleation at the centrosome

The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

ING1 Polyclonal Antibody, 50ul PCR Series and to lead to NF-kappaBThis gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

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