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Aquaporin 4 Monoclonal Antibody(4H1), 100ul Miscellaneous Alternative splicing results in multiple

SKU: 21013979232

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Aquaporin 4 Monoclonal Antibody(4H1), 100ul Miscellaneous Alternative splicing results in multipleThis gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene

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Description

Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1

Since both phosphorylation and glycosylation compete for similar serine or threonine residues| the two processes may compete for sites| or they may alter the substrate specificity of nearby sites by steric or electrostatic effects

including one with a novel exon that is generated by RNA editing

This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA)

The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line

Aquaporin 4 Monoclonal Antibody(4H1), 100ul Miscellaneous Alternative splicing results in multipleThis gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene

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