Frizzled-1 Polyclonal Antibody, 50ul[BT-AP15675] Custom Peptide Synthesis and is found in either

and is found in either a latent form composed of a mature peptide homodimer

each possessing transmembrane regions

has also been studied because of its expression in human tumors

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12

Frizzled-1 Polyclonal Antibody, 50ul[BT-AP15675] Custom Peptide Synthesis and is found in eitherMembers of the 'frizzled' gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine rich domain in the N terminal extracellular region, 7 transmembrane domains, and a C terminal PDZ domain binding motif. The FZD1 transcript is expressed in various tissues.