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LOXL4 Rabbit Polyclonal Antibody, 50ul Mechanical Pipette Also acts by promoting PIK3R1/p85

SKU: 21127230647

4.1
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LOXL4 Rabbit Polyclonal Antibody, 50ul Mechanical Pipette Also acts by promoting PIK3R1/p85This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain

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Description

Also acts by promoting PIK3R1/p85 ubiquitination

6-biphosphate using independent catalytic domains

Mutations in this gene cause Gitelman syndrome| a disease similar to Bartter's syndrome| that is characterized by hypokalemic alkalosis combined with hypomagnesemia| low urinary calcium| and increased renin activity associated with normal blood pressure

the interaction is direct and specific for CENPA since it does not interact with H3

Members of the leucine-rich GPCR (LGR) family

LOXL4 Rabbit Polyclonal Antibody, 50ul Mechanical Pipette Also acts by promoting PIK3R1/p85This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain

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