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NPM(Phospho-Thr95) Rabbit Polyclonal Antibody, 20ul In vitro Assessment POLR1E (Polymerase (RNA) I Subunit

SKU: 21187505866

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NPM(Phospho-Thr95) Rabbit Polyclonal Antibody, 20ul In vitro Assessment POLR1E (Polymerase (RNA) I SubunitThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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Description

POLR1E (Polymerase (RNA) I Subunit E) is a Protein Coding gene

Transcription of this gene increases upon virus induction

and trapping it in the cytoplasm

Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity

RAD50 double strand break repair protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends

NPM(Phospho-Thr95) Rabbit Polyclonal Antibody, 20ul In vitro Assessment POLR1E (Polymerase (RNA) I SubunitThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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