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ZIP4 Polyclonal Antibody, 50ul Aspirating Pipets subcellular location:Distributed throughout the cytoplasm

SKU: 21273638433

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ZIP4 Polyclonal Antibody, 50ul Aspirating Pipets subcellular location:Distributed throughout the cytoplasmSLC39A4 (solute carrier family 39 member 4) encodes a member of the zinc iron regulated transporter like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in SLC39A4 result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for SLC39A4.

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Description

subcellular location:Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells

and gene expression

The encoded protein is covalently conjugated to other proteins via a post-translation modification known as sumoylation

The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and

Studies in mouse suggest that it may be involved in osteo- and chondrogenic differentiation

ZIP4 Polyclonal Antibody, 50ul Aspirating Pipets subcellular location:Distributed throughout the cytoplasmSLC39A4 (solute carrier family 39 member 4) encodes a member of the zinc iron regulated transporter like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in SLC39A4 result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for SLC39A4.

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