Op18 Polyclonal Antibody, 50ul[BT-AP06571] Monoclonal Antibody Preparation have been implicated in a

have been implicated in a number of developmental and neurogenetic diseases such as microcephaly

An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4)| a protein containing two fibronectin type III domains

mental retardation and cancer

Additional transcript variants have been described

E3 SUMO-protein ligase component of the SMC5-SMC6 complex

Op18 Polyclonal Antibody, 50ul[BT-AP06571] Monoclonal Antibody Preparation have been implicated in aSTMN1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for STMN1.