MMP8 (Cleaved-Leu101) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection It is selectively expressed in

It is selectively expressed in reactive stromal fibroblasts of epithelial cancers

The protein encoded by UMOD (uromodulin) is the most abundant protein in mammalian urine under physiological conditions

Among its related pathways are mRNA Splicing - Major Pathway

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins

It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets

MMP8 (Cleaved-Leu101) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection It is selectively expressed inCatalytic activity: Cleavage of interstitial collagens in the triple helical domain. Unlike EC 3. 4. 24. 7 this enzyme cleaves type III collagen more slowly than type I. cofactor: Binds 2 zinc ions per subunit. cofactor: Binds 3 calcium ions per subunit. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation peptide