Rb Polyclonal Antibody, 20ul[BT-AP07687] Vortex Mixer Misshapen-like kinase 1 is structurally

Misshapen-like kinase 1 is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins

which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits

No adsorption of cytokines or growth factors

The ARF4 gene spans approximately 12kb and contains six exons and five introns

Rb Polyclonal Antibody, 20ul[BT-AP07687] Vortex Mixer Misshapen-like kinase 1 is structurallyThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.