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Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma It possesses at least two

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Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma It possesses at least twoThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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Description

It possesses at least two conserved domains that could be important for its function

This gene encodes the alpha chain of type XII collagen

Alternative splicing may result in several transcript variants

Catalytic activity:Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus| at 775-Gly-|-Ile-776 in the alpha-1(I) chain

The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs)| which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins (Shimomura et al

Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma It possesses at least twoThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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