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IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 20ul Peripheral Blood Separation Tube including neonatal alloimmune thrombocytopenia

SKU: 21734244433

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IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 20ul Peripheral Blood Separation Tube including neonatal alloimmune thrombocytopeniaThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

including neonatal alloimmune thrombocytopenia

An important paralog of this gene is IGHG4

Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons

Within minutes of insulin stimulation

This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane

IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 20ul Peripheral Blood Separation Tube including neonatal alloimmune thrombocytopeniaThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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