ANO5 Rabbit Polyclonal Antibody, 50ul ADME Loss of function of this

Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability

Also expressed in certain liver and kidney carcinomas

The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins)

all three variants encode the same protein

May exert this function by promoting GLI1 nuclear localization

ANO5 Rabbit Polyclonal Antibody, 50ul ADME Loss of function of thisThis gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described.