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IκB-alpha Polyclonal Antibody, 20ul Recombinant Ab Production membrane-associated proteins that recruit effector

SKU: 21780113756

4.2
USD97.20 USD122.20

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IκB-alpha Polyclonal Antibody, 20ul Recombinant Ab Production membrane-associated proteins that recruit effectorThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state

enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

This protein plays a central role in exerting IL4 mediated biological responses

Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids

IκB-alpha Polyclonal Antibody, 20ul Recombinant Ab Production membrane-associated proteins that recruit effectorThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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