Survivin Polyclonal Antibody, 20ul[BT-AP01683] Thermo Mix ITGA3 (integrin subunit alpha 3)

ITGA3 (integrin subunit alpha 3) encodes a member of the integrin alpha chain family of proteins

most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development

a soluble form (S-COMT) and a membrane-bound form (MB-COMT)

Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes

the encoded protein is sequestered in the cytoplasm

Survivin Polyclonal Antibody, 20ul[BT-AP01683] Thermo Mix ITGA3 (integrin subunit alpha 3)This gene is a member of the inhibitor of apoptosis (IAP) gene family which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues.