OPA1 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Integrins are heterodimeric integral membrane

Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion

A mutation in this gene has been shown to result in polyhydramnios

|Belongs to the peptidase S1 family

it is required to recruit USP22 and ENY2 into the SAGA complex

The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism

OPA1 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Integrins are heterodimeric integral membraneThis gene product is a nuclear encoded mitochondrial protein with similarity to dynamin related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.