Vav1(Phospho Tyr174) Polyclonal Antibody, 100ul Reagent Reservoirs The protein encoded by this

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family

slow- and cardiac-type isoforms

Mutations in this gene cause pseudoxanthoma elasticum

Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins

bone marrow and peripheral blood leukocytes

Vav1(Phospho Tyr174) Polyclonal Antibody, 100ul Reagent Reservoirs The protein encoded by thisThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.