IMP-3 Monoclonal Antibody, 100ul Monoclonal Antibodies tissue specificity:Expressed in fetal and

tissue specificity:Expressed in fetal and adult skeletal muscle

KDELR3 was the third member of the family to be identified

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

Guanine nucleotide exchange factor (GEF) for Rap1A

The product of this gene functions in the nucleotide excision repair pathway

IMP-3 Monoclonal Antibody, 100ul Monoclonal Antibodies tissue specificity:Expressed in fetal andThe protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin like growth factor II leader 3 mRNA and may repress translation of insulin like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative