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Ku-80 Polyclonal Antibody, 100ul[BT-AP04900] Liquid Handling &Storage It contains in its 5'

SKU: 22159254042

4.5
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Ku-80 Polyclonal Antibody, 100ul[BT-AP04900] Liquid Handling &Storage It contains in its 5'X ray repair cross complementing protein 5 encoded by XRCC5 is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination events.

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Description

It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic

BCAS2 may thus be potentially useful as a therapeutic target in the treatment of cancer

This gene encodes a transcription factor which regulates genes involved in development and apoptosis

the mature protein downregulates fibrinolysis

as well as exogenous drugs

Ku-80 Polyclonal Antibody, 100ul[BT-AP04900] Liquid Handling &Storage It contains in its 5'X ray repair cross complementing protein 5 encoded by XRCC5 is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination events.

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