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O-FucT-1 Polyclonal Antibody, 20ul Liquid Handling &Storage Heparanase encoded by HPSE is

SKU: 22588061832

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O-FucT-1 Polyclonal Antibody, 20ul Liquid Handling &Storage Heparanase encoded by HPSE isPOFUT1 encodes a member of the glycosyltransferase O Fuc family. This enzyme adds O fucose through an O glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor like repeats of a number of cell surface and secreted proteins. O fucose glycans are involved in ligand induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

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Description

Heparanase encoded by HPSE is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix

CEP70 is involved in organizing microtubules in interphase cells and is required for proper organization and orientation of the mitotic spindle

The precursor seems to be activated while it is being transported along the axon to the posterior pituitary

Tissue-specific utilization of alternative polyA-signal has been described in literature

The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction

O-FucT-1 Polyclonal Antibody, 20ul Liquid Handling &Storage Heparanase encoded by HPSE isPOFUT1 encodes a member of the glycosyltransferase O Fuc family. This enzyme adds O fucose through an O glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor like repeats of a number of cell surface and secreted proteins. O fucose glycans are involved in ligand induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

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