Nanog Monoclonal Antibody, 100ul Recombinant Protein Expression Three transcript variants encoding different

Three transcript variants encoding different isoforms have been found for ACTN1

This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains

as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases

Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling

Nanog Monoclonal Antibody, 100ul Recombinant Protein Expression Three transcript variants encoding differentThe protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene.