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Phospho-ARK-1 (S342) Polyclonal Antibody, 50ul 3D Culture The SART1(259) protein is translated

SKU: 22813523304

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SEK162.00 SEK202.00

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Phospho-ARK-1 (S342) Polyclonal Antibody, 50ul 3D Culture The SART1(259) protein is translatedThe protein encoded by AURKA (aurora kinase A) is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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Description

The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation

suggesting that this kinase may serve as an intermediate in the response to cellular stress

Has a major role in establishing the blood-brain barrier (By similarity)

Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)

and thus catalyze the first step in digestion of dietary starch and glycogen

Phospho-ARK-1 (S342) Polyclonal Antibody, 50ul 3D Culture The SART1(259) protein is translatedThe protein encoded by AURKA (aurora kinase A) is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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