LRRK2 Polyclonal Antibody, 20ul Cell Transfection Several alternatively spliced transcripts have

Several alternatively spliced transcripts have been described

ERF2/ZDHHC9 subfamily

Multiple transcript variants encoding different isoforms have been found for MYO9B

The protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA

It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome

LRRK2 Polyclonal Antibody, 20ul Cell Transfection Several alternatively spliced transcripts haveThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.