p40-phox(Phospho Thr154) Polyclonal Antibody, 20ul Lentiviral Packaging Allelic variants of this gene

Allelic variants of this gene have been associated with autism and addiction vulnerability

Its function in proximal tubular epithelial cells and other cell types is less clear

This gene is a member of the regulatory factor X gene family| which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain

the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation

The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters

p40-phox(Phospho Thr154) Polyclonal Antibody, 20ul Lentiviral Packaging Allelic variants of this geneThe protein encoded by this gene is a cytosolic regulatory component of the superoxide producing phagocyte NADPH oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2 p67 phox) to form a complex with neutrophil cytosolic factor 1 (NCF1 p47 phox), which further interacts with the small G protein RAC1 and