Phospho-AP-1 (T93) Polyclonal Antibody, 100ul Low retention tips subunit:Heterotetramer

subunit:Heterotetramer

This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1)

The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling

The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis

Additional splicing is suggested but complete sequence for further transcripts has not been determined

Phospho-AP-1 (T93) Polyclonal Antibody, 100ul Low retention tips subunit:HeterotetramerJUN is the putative transforming gene of avian sarcoma virus 17. It encodes Jun proto oncogene, AP 1 transcription factor subunit which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.