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GSTK1 Rabbit Polyclonal Antibody, 50ul Microplate Mixer The immunoproteasome contains an alternate

SKU: 23119894221

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GSTK1 Rabbit Polyclonal Antibody, 50ul Microplate Mixer The immunoproteasome contains an alternateThis gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.

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Description

The immunoproteasome contains an alternate regulator| referred to as the 11S regulator or PA28| that replaces the 19S regulator

The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles

These domains have been shown to bind extracellular matrix proteins

This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family

Ubiquitination has been associated with protein degradation| DNA repair| cell cycle regulation| kinase modification| endocytosis| and regulation of other cell signaling pathways

GSTK1 Rabbit Polyclonal Antibody, 50ul Microplate Mixer The immunoproteasome contains an alternateThis gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.

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