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RARA Polyclonal Antibody, 20ul Vector Construction 2004 [PubMed 15363391])

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RARA Polyclonal Antibody, 20ul Vector Construction 2004 [PubMed 15363391])This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants

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Description

2004 [PubMed 15363391])

Among its related pathways are Actin Nucleation by ARP-WASP Complex and PAK Pathway

Each of these similar proteins

The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding

The N-terminal FADD-like death effector domain of Caspase 8 suggests that it may interact with Fas-interacting protein FADD

RARA Polyclonal Antibody, 20ul Vector Construction 2004 [PubMed 15363391])This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants

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