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BubR1 Polyclonal Antibody, 50ul 3D Culture which excises the activation peptide

SKU: 23174830955

4.4
EUR185.00 EUR211.00

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BubR1 Polyclonal Antibody, 50ul 3D Culture which excises the activation peptideBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

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Description

which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium

One of several members of the Ser/Thr protein kinase family

including the hexadecapeptide

The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al

BubR1 Polyclonal Antibody, 50ul 3D Culture which excises the activation peptideBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

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