IKappaB- Alpha Polyclonal Antibody, 100ul[BT-AP04672] Syringe Filter The phosphodiesterase 10A encoded by

The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family

including virus-mediated activation of interferon

Component of the NF-kappa-B p105-p50 complex

• Speed range of 100-350 rpm

200 residues at the N-terminus (domains IV

IKappaB- Alpha Polyclonal Antibody, 100ul[BT-AP04672] Syringe Filter The phosphodiesterase 10A encoded byNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. NF kappa B inhibitor alpha interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. NF kappa B inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic