SENP5 Polyclonal Antibody, 100ul Organelle Studies function in intracellular transport
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SENP5 Polyclonal Antibody, 100ul Organelle Studies function in intracellular transportThe reversible posttranslational modification of proteins by the addition of small ubiquitin like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO
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