Histone H4 (Acetyl Lys16) Polyclonal Antibody, 50ul[BT-AP04101] Funnels Multiple heterogeneous transcriptional start sites

Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported

FZD7 expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas

as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants

In response to BMP ligands

Its substrates are however unknown

Histone H4 (Acetyl Lys16) Polyclonal Antibody, 50ul[BT-AP04101] Funnels Multiple heterogeneous transcriptional start sitesHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.