ATR Polyclonal Antibody, 100ul Thermal Control Mitotic cyclins stably associate with

Mitotic cyclins stably associate with this protein and function as regulatory subunits

including this gene product

sequence-specific DNA binding and transcriptional activator activity

Members of this protein family have an affinity for beta-galactosides

Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini

ATR Polyclonal Antibody, 100ul Thermal Control Mitotic cyclins stably associate withThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,