FILA2 Rabbit Polyclonal Antibody, 100ul Molecular Sciences small GTP binding protein Rac1)

small GTP binding protein Rac1) encoded by RAC1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins

Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma catalyzes phosphorylation of phosphatidylinositol 4-phosphate

Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and PDZ domain binding

Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins

Different markings at the head and end of the joint cap for easy identification of direction

FILA2 Rabbit Polyclonal Antibody, 100ul Molecular Sciences small GTP binding protein Rac1)The filaggrin like protein encoded by this gene is upregulated by calcium proteolyzed by calpain 1 and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact in addition to providing a physical barrier C terminal fragments of this protein display antimicrobial activity