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Neurofibromin Polyclonal Antibody, 20ul Mini dry bath thyroid hormone receptor-(TR-) associated proteins

SKU: 23955038905

4.5
USD97.20 USD135.20

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Neurofibromin Polyclonal Antibody, 20ul Mini dry bath thyroid hormone receptor-(TR-) associated proteinsNF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA >Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

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Description

thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors

which is a common gamma chain shared by the receptors of various cytokines

Chromosomal translocations involving CREBBP have been associated with acute myeloid leukemia

atrial fibrillation

such as epithelial cells

Neurofibromin Polyclonal Antibody, 20ul Mini dry bath thyroid hormone receptor-(TR-) associated proteinsNF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA >Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

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