DRAM1 Polyclonal Antibody, 50ul Serological Pipets STXBP1 (syntaxin binding protein 1)

STXBP1 (syntaxin binding protein 1) encodes a syntaxin-binding protein

which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes

This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis

Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and serotonin binding

DRAM1 Polyclonal Antibody, 50ul Serological Pipets STXBP1 (syntaxin binding protein 1)This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.