PLB Polyclonal Antibody, 100ul Immunology It is localized to the

It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region

when complexed to CAK

The ROS generated by family members have been implicated in numerous biological functions including host defense

as well as KRTHB3 and KRTHB6

Pseudogenes of this gene have been defined on chromosomes 14 and 17

PLB Polyclonal Antibody, 100ul Immunology It is localized to theThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the