FOSL2 Polyclonal Antibody, 100ul Variant Libraries Mutations in this gene are

Mutations in this gene are associated with susceptibility to obesity in humans

DUF1220 copy number variations in human chromosomal region 1q21

A related pseudogene of this gene is found on chromosome X

PIAS2 encodes a member of the protein inhibitor of activated STAT (PIAS) family

resulting in increased GLUT4 at the cell surface

FOSL2 Polyclonal Antibody, 100ul Variant Libraries Mutations in this gene areThe Fos gene family consists of 4 members: fOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.