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Rb(Phospho Ser795) Polyclonal Antibody, 20ul Pipette Controller Minichromosome maintenance complex component 3

SKU: 24162798593

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Rb(Phospho Ser795) Polyclonal Antibody, 20ul Pipette Controller Minichromosome maintenance complex component 3The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Minichromosome maintenance complex component 3 encoded by MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

have been identified

radiomimetic chemicals

Belongs to the calmodulin family

After binding acetylcholine| the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane

Rb(Phospho Ser795) Polyclonal Antibody, 20ul Pipette Controller Minichromosome maintenance complex component 3The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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