MEK-2 Polyclonal Antibody, 50ul[BT-AP11254] Peripheral Blood Separation Tube Cleavage of the alpha chain

Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin

Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam

and the protein itself is processed by caspases 8

Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor

Disruption of LIG1 may also be associated with a variety of cancers

MEK-2 Polyclonal Antibody, 50ul[BT-AP11254] Peripheral Blood Separation Tube Cleavage of the alpha chainThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1 ERK2 and MAPK2 ERK3. The activation of this kinase itself is dependent on the Ser Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC