CC147 Rabbit Polyclonal Antibody, 20ul Nucleic Acid Amplification CLIC6 is part of a

CLIC6 is part of a large triplicated region found on chromosomes 1

Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E| gamma-F| gamma-G) are tandemly organized in a genomic segment as a gene cluster

Members of this family form the core of a highly conserved tumor suppressor network

an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression

Constitutive activation of this gene caused either by somatic mutations| or genomic duplications of regions that include this gene| have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome

CC147 Rabbit Polyclonal Antibody, 20ul Nucleic Acid Amplification CLIC6 is part of a