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Fes Monoclonal Antibody, 100ul[BT-MCA0531] Vacuum Aspirator Upon erythropoietin binding

SKU: 24256176476

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Fes Monoclonal Antibody, 100ul[BT-MCA0531] Vacuum Aspirator Upon erythropoietin bindingThis gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth

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Description

Upon erythropoietin binding

It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin

Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase

CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform

Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control

Fes Monoclonal Antibody, 100ul[BT-MCA0531] Vacuum Aspirator Upon erythropoietin bindingThis gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth

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