FAT10 Polyclonal Antibody, 100ul General Lab Use Inhibits differentiation of CD34+ cell

Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro)

which may be important for neoplastic transformation and tumor progression

some of which are associated with Creutzfeldt-Jakob disease

is amplified in the mouse transformed 3T3 cell line

This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex

FAT10 Polyclonal Antibody, 100ul General Lab Use Inhibits differentiation of CD34+ cellFAT10, also designated Ubiquitin D or Diubiquitin, is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin. Each domain contains two cysteines, along with a free C terminal diglycine motif required for FAT10 conjugate formation. FAT10 is inducible by interferon g and tumor necrosis factor a (TNF). The FAT10 protein interacts with MAD2, a component of