Human Rho Guanine Nucleotide Exchange Factor 4, ARHGEF4 ELISA Kit, 96T Vessels Mutations affecting the coding region

Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS)

there are multiple processed pseudogenes of RPS11 dispersed throughout the genome

Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

with lower levels found in lung and brain

is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1

Human Rho Guanine Nucleotide Exchange Factor 4, ARHGEF4 ELISA Kit, 96T Vessels Mutations affecting the coding region