NFATc2IP Polyclonal Antibody, 100ul Peptide Library PLCB2 (Phospholipase C Beta 2)

PLCB2 (Phospholipase C Beta 2) is a Protein Coding gene

thus is thought to be a candidate tumor suppressor gene

The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA)

This gene encodes a member of the syntaxin superfamily

There are multiple isoforms of each of the proteins in the complex

NFATc2IP Polyclonal Antibody, 100ul Peptide Library PLCB2 (Phospholipase C Beta 2)NFATC2IP, also named as NIP45, is a 419 amino acid protein, which contains one ubiquitin like domain. TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. NFATC2IP In T helper 2 (Th2) cells, regulates the magnitude of NFAT driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2.