Mi2- Alpha Monoclonal Antibody, 100ul[BT-MCA0885] Cell Labeling & Imaging Diseases associated with CADM1 include

Diseases associated with CADM1 include asthenopia and lung cancer

|PTM:Subsequent to MAP3K14-dependent serine phosphorylation| p100 polyubiquitination occurs then triggering its proteasome-dependent processing

Interacts with PCNT

Mutations in DOK7 are a cause of familial limb-girdle myasthenia autosomal recessive

The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis

Mi2- Alpha Monoclonal Antibody, 100ul[BT-MCA0885] Cell Labeling & Imaging Diseases associated with CADM1 includeThis gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2 related helicase ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi 2 NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription.