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Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development which bind to orphan G-protein

SKU: 24919158642

4.3
USD162.00 USD198.00

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Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development which bind to orphan G-proteinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2

Gene Ontology (GO) annotations related to this gene include calmodulin binding and Ras GTPase binding

A pseudogene of this gene is found on chromosome 13

9 PCR Tube Adapter

Peutz-Jeghers syndrome

Rb Polyclonal Antibody, 50ul[BT-AP07694] Antibody Development which bind to orphan G-proteinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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