IRS2 Polyclonal Antibody, 50ul ssDNA Synthesis May bind polyunsaturated fatty acids

May bind polyunsaturated fatty acids

Mutations in this gene have been associated with bone marrow failure syndrome 2

They are also characterized by a catalytic triad composed of a histidine

Alternative splicing results in multiple transcript variants encoding the same protein

The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene

IRS2 Polyclonal Antibody, 50ul ssDNA Synthesis May bind polyunsaturated fatty acidsIRS2 (insulin receptor substrate 2) encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of IRS2 is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor associated