ETS1 Monoclonal Antibody, 50ul[BT-MCA0522] Cell Separation and Collection Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for CHEK2

HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA)

the short isoform(14 kDa) has been shown to repress gamma-globin gene expression

it has only a single zinc finger module

The encoded protein has been implicated in several pathologic processes

ETS1 Monoclonal Antibody, 50ul[BT-MCA0522] Cell Separation and Collection Several transcript variants encoding differentThis gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA binding domain that recognizes the core consensus DNA sequence GGAA T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding