PKC Alpha Polyclonal Antibody, 50ul[BT-AP07209] Metabolic enzymes tool compounds Increased expression of this gene

Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling

and is thought to be specifically chemotactic for T cells

This gene has been found to be a tumor suppressor and an oncogene| depending on the context

Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma

Pseudogenes corresponding to this gene are found on chromosomes 3p

PKC Alpha Polyclonal Antibody, 50ul[BT-AP07209] Metabolic enzymes tool compounds Increased expression of this geneProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile